Figure 2
The exquisite sensitivity of neutrons as a probe for determining the protonation states of histidine, a frequent player in enzyme mechanisms. Left, His24 singly protonated; right, His180 doubly protonated histidine in concanavalin A (PDB code 2yz4; Ahmed et al., 2007). This figure was made with Coot (Emsley & Cowtan, 2004). |