Figure 4
The crystal packing of (II), showing four fexofenadine dimers and the solvent water molecules (small spheres). Hydrogen bonds are denoted by dashed lines. H atoms have been omitted for clarity. The dimeric entities are distributed between two different continuously hydrogen-bonded layers formed in the crystal which are centered at x = 0 and x = 1. At the interface between the layers (at x = ), the diphenylmethyl embraces provide the stabilizing van der Waals interaction. |