Figure 3
The common structural unit of the compounds listed in Table 1 and definition of the torsion angles T1 and T2 for acemetacin [R = –CH2C(=O)OCH2COOH and hal = Cl], indomethacin (R = –CH2COOH and hal = Cl), iodoindomethacin (R = –CH2COOH and hal = I) and indomethacin methyl ester (R = –CH2COOMe and hal = Cl). |