Figure 3
A superposition of the molecular conformations of the sorafenib molecules. The overlay was produced by making a least-squares fit of the central planar six-membered ring atoms with those of (I). The labels are as follows: (II) is sorafenib tosylate; 3 is PDB code 3GCS; 4 is 3HEG; 5 is 1UWH (molecule 1); 6 is 1UWH (molecule 2). |