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Figure 5
Superposition of the molecular conformations of the tapentadol molecules of (I) and (IV) , showing the orientations of the ethyl and aminopropyl groups with respect to the phenol ring. The overlay was made by making a least-squares fit through the planar phenol ring (atoms C1–C7) of tapentadol [molecules (IA) and (IB) ] and (IV) . |


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