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Figure 4
The superposition of the conformations of the cations in (I)[link], (II)[link], the optimized structure (labelled as 3) and the lapatinib–EGFR complex (4), showing the orientation difference of the substituents at atoms C14 and C25. The overlay was made by making a least-squares fit through the quinazoline ring system of (I)[link].

Journal logoSTRUCTURAL
CHEMISTRY
ISSN: 2053-2296
Volume 69| Part 12| November 2013| Pages 1516-1523
doi:10.1107/S0108270113028965
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