Figure 8
A view of the extensive hydrogen-bonding scheme in (V) between the drug molecule itself and the two waters of hydration and the hydronium chloride (making the hydroxonium ion H7O3+). Note the extensive network of hydrogen-bonded hydronium cations and waters, where the chlorides provide additional anchoring points to the ammonium cationic drug. The network propagates infinitely throughout the crystal; what is shown here is only a small segment. |