Figure 10
Base-pairing motifs of 5-aza-7-deazaguanine nucleosides, pKa values of the base-pairing nucleosides and their pK value difference (ΔpK), as well as strand orientation of the respective duplex. Notes: R = β-D-ribofuranosyl, C = cytidine, iG = isoguanosine, iC = isocytidine, G = guanosine, c7G = 7-deazaguanosine, aps = antiparallel strands and ps = parallel strands. |