Figure 9
Projection of the structures of 4 (standard colour) and 6 (green) along the b axis. The highlighted N—CH3⋯π interaction in 4 [C2S⋯centroid(C5–C10) = 3.825 Å] causes the celecoxib molecules to rotate outwards relative to each other, as indicated by the thick arrows, causing expansion and skewing of the unit cell compared to 6. |