Polymorphism in a secondary phosphine

Two crystal structures of bis­(2,3,5,6-tetra­methyl­phen­yl)phosphine, C₂₀H₂₇P, are reported constituting the first recorded case of polymorphism in a secondary phosphine (R₂PH). The two structures differ in their conformation and, as a result, the steric hindrance experienced at the phospho­rus centre is observed to be dependent on the packing environment. Each polymorph exhibits a distinct supra­molecular structure; in polymorph I the mol­ecules are arranged in columns in two directions, whereas polymorph II forms layers. There is a distinct lack of significant inter­molecular inter­actions in either form, with the exception of some weak Me⋯π inter­actions observed in polymorph II. These inter­actions are likely the cause of the variation in the C—P—C angles observed between the two structures.

1. Introduction

Phosphines have become ubiquitous ligands for transition-metal centres due to the ease with which their electronic and steric properties may be tailored and to the many and varied applications of transition-metal phosphine com­plexes in catal­y­sis. Secondary phosphines R₂PH have the added advantage that the P—H proton may readily be removed to furnish anionic phosphanide R₂P⁻ ligands (Izod, 2000). We have a long-standing inter­est in the application of such phos­phanide ligands for the support of novel low-oxidation-state main group species; for example, the recently isolated fully phosphanyl-substituted ditetrelenes {(Mes)₂P}₂E=E{P(Mes)₂}₂ (E = Si or Ge; Mes = 2,4,6-Me₃C₆H₂) (Izod et al., 2017a, 2022).

In the course of this work, we have striven to explore the impact of the steric profile and substitution pattern of the aromatic rings in di­aryl­phosphanide ligands on the structures and stabilities of both low-oxidation-state main group com­pounds and their alkali metal precursors R₂PM (M = Li, Na or K) (Izod et al., 2017b). While 2,6-disubstituted and 2,4,6-tri­sub­stituted aromatic rings are common phosphine substituents, alternative substitution patterns, such as in the 2,3,5,6-tetra­methyl­phenyl substituent described here, are rare.

Due to their reactivity, the structure determination of sec­ondary phosphines using single-crystal X-ray crystallography can be challenging, with the first such structure being reported in 1987 (Bartlett et al., 1987). As testament to this, at time of writing there are only 95 organic acyclic secondary phosphine structures in the Cambridge Structural Database (CSD, Ver­sion 5.45, update 2, June 2024; Groom et al., 2016) and only one polymorph is reported for any one secondary phosphine com­pound, including cyclic phosphines and organometallic com­plexes.

In this work, we present the first known instance of polymorphism in a secondary phosphine. Bis(2,3,5,6-tetra­methyl­phen­yl)phosphine (Fig. 1) crystallizes in two distinct forms: polymorph I, grown from tetra­hydro­furan, which crystallizes in the monoclinic space group P2/n, and polymorph II, grown from fluoro­benzene, which crystallizes in the monoclinic space group P2₁/c. As the first case of its kind, the structural analysis here should provide unique insights into the supra­molecular chemistry of secondary phosphines.

Figure 1 Bis(2,3,5,6-tetra­methyl­phen­yl)phosphine with the numbering scheme used in this article.

2. Experimental

2.1. Preparation of bis­(2,3,5,6-tetra­methyl­phen­yl)phosphine

All manipulations were performed under an inert atmosphere (argon gas) using standard Schlenk techniques unless otherwise stated. To a cold (−78 °C) solution of PCl₃ (2.9 ml, 23 mmol) in diethyl ether (50 ml) was added (2,3,5,6-Me₄C₆H)MgBr (42 mmol) dissolved in tetra­hydro­furan (THF, 200 ml). This mixture was allowed to warm to room tem­per­a­ture and was stirred for 12 h. To this solution was carefully added an excess of solid LiAlH₄ (1.0 g, 26.3 mmol) and the resulting mixture was stirred at room tem­per­a­ture for 2 h. Degassed water (50 ml) was carefully added and the organic phase was extracted into THF (3 × 30 ml). The combined organic extracts were dried over activated 4 Å mol­ecular sieves, the solution was filtered and solvent was removed in vacuo from the filtrate to give bis­(2,3,5,6-tetra­methyl­phen­yl)phosphine as a colourless solid in 65% yield. Crystals suitable for single-crystal X-ray diffraction were grown from cold (3 °C) THF (polymorph I) or from cold (−30 °C) fluoro­benzene (polymorph II).

2.2. Refinement

Crystal data, data collection and structure refinement details are summarized in Table 1. H atoms bound to C atoms were positioned with idealized geometry. The displacement parameters of these H atoms were constrained using a riding model, with U_iso(H) values set to be an appropriate multiple of the U_eq value of the parent atom.

Table 1
Experimental details

For both structures: C₂₀H₂₇P, M_r = 298.38. Experiments were carried out at 150 K with Cu Kα radiation using a Rigaku Xcalibur Gemini ultra diffractometer with an Atlas detector. The absorption correction was analytical [CrysAlis PRO (Rigaku OD, 2015), based on expressions derived by Clark & Reid (1995)]. H atoms were treated by a mixture of independent and constrained refinement.

	Polymorph I	Polymorph II
Crystal data
Crystal system, space group	Monoclinic, P2/n	Monoclinic, P21/c
a, b, c (Å)	6.5476 (2), 5.9910 (2), 21.5676 (6)	12.8874 (6), 8.8455 (3), 15.4635 (7)
β (°)	96.020 (2)	104.108 (5)
V (Å^3)	841.36 (4)	1709.61 (13)
Z	2	4
μ (mm^−1)	1.35	1.33
Crystal size (mm)	0.24 × 0.08 × 0.06	0.36 × 0.14 × 0.05
Data collection
Tmin, Tmax	0.696, 0.866	0.746, 0.939
No. of measured, independent and observed [I > 2σ(I)] reflections	11409, 1500, 1299	12709, 3021, 2424
Rint	0.040	0.039
(sin θ/λ)max (Å^−1)	0.596	0.596
Refinement
R[F^2 > 2σ(F^2)], wR(F^2), S	0.039, 0.118, 1.06	0.047, 0.135, 1.06
No. of reflections	1500	3021
No. of parameters	103	214
No. of restraints	0	182
Δρmax, Δρmin (e Å^−3)	0.27, −0.24	0.43, −0.35
Computer programs: CrysAlis PRO (Rigaku OD, 2015), SHELXT (Sheldrick, 2015a), SHELXL (Sheldrick, 2015b) and OLEX2 (Dolomanov et al., 2009).

The H atoms bound to phospho­rus were located using peaks in the Fourier difference map. In both structures, the most prominent residual peaks about phospho­rus after all other atoms were modelled were selected. In the case of polymorph I, the occupancy of this H atom was constrained to be 0.5 as it is disordered across a special position. For polymorph II, peaks corresponding to two proton positions with similar geometry were observed and hence the phosphine H atom was split across two positions with the occupancies refined to be approximately 63 and 37%. The displacement parameters of the phosphine H atoms in both structures were constrained using a riding model, with U_iso(H) values set to be 1.2U_eq relative to the parent atom.

It is likely that the unrestrained P—H distances are shorter than the true bond lengths, but the direction of the bond vectors are likely to be accurate. Though some residual density remains, most prominently in the structure of polymorph II, there are no peaks greater than 0.5 e Å⁻³ and they do not appear to be in positions that could correspond to atoms; the largest peak is altogether too close to the P atom (<1 Å) and/or in a position that would make little sense in terms of mol­ecular geometry. It is possible that these residual peaks are the result of series termination errors (Fourier ripples).

3. Results and discussion

The two structures of bis­(2,3,5,6-tetra­methyl­phen­yl)phosphine crystallize in different monoclinic space groups. Polymorph I crystallizes in the space group P2/n, with an asymmetric unit com­prising half of the mol­ecule (Z′ = 0.5). Here the P atom is located on the twofold rotation axis in the structure and the full mol­ecule is generated through this symmetry operation. Polymorph II crystallizes in the space group P2₁/c, with one whole mol­ecule in the asymmetric unit. In both structures, the proton on the P atom is disordered over two positions, as has been observed previously in similar bis­(ar­yl) secondary phosphine structures (Izod et al., 2017b; Clegg, 2017). Details of the refinements for both structures are presented in Table 1.

Though the bond distances do not differ significantly, the conformations of the mol­ecules in the two polymorphs are somewhat different, as demonstrated by overlaying them (Fig. 2). The conformational variation can be attributed to differences in the geometry about the P atom and the angles between the planes of the aryl rings (Table 2). As polymorph I exhibits a wider C—P—C angle than polymorph II, this would suggest that it experiences a greater degree of steric hindrance at the phospho­rus centre (Rivard et al., 2007).

Table 2
Selected geometric parameters (Å, °) for polymorphs I and II

	Polymorph I	Polymorph II
P1—C1	1.8471 (17)	1.852 (2)
P1—C11		1.856 (2)
C1—P1—C1/11	108.78 (11)	105.74 (9)
C1—P1—H1	100 (2)	109.1 (2)
C1—P1—H1^i/C11—P1—H1	99 (2)	118.4 (2)
Ar­yl–aryl twist angle	84.39 (10)	94.12 (9)
Symmetry code: (i) −x + , y, −z + .

Figure 2 Overlay diagram of polymorphs I (yellow) and II (green).

The degree of steric pressure on the P atom in bis­(ar­yl)phosphines can also be assessed by the sum of the angles about phospho­rus, Σ°P (Boeré & Zhang, 2005). The values measured exceed 300°, with polymorph I exhibiting a Σ°P of 318 (2)° and the same sum being 333.2 (2)° for polymorph II (measured for the H atom of highest occupancy). This would seem to contradict the inter­pretation of the C—P—C bond angles as, according to the Σ°P, the P atom in polymorph II is under greater steric pressure in spite of its narrower C—P—C angle. Regardless of the trend in these measurements, that there should be such variation within the same mol­ecule demonstrates the effect that polymorphism can potentially have on these com­pounds. These conformational perturbations are likely the result of the different packing environments and inter­molecular inter­actions in the two solid-state structures.

As is common in the structures of secondary bis­(ar­yl)phosphines, there are no significant contacts involving the H atom on the phospho­rus in either structure (Izod et al., 2017b; Bartlett et al., 1987; Clegg, 2017; Rivard et al., 2007; Fleming et al., 2013; Ritch et al., 2014). The lack of structure-directing inter­actions involving this atom may well be the root of the disorder of the P—H proton manifest in both polymorphs.

The packing in both structures seems to prioritize the minimization of steric inter­actions as opposed to forming strong structure-directing inter­molecular bonds. As such, the packing is best described in terms of the alignment of the aryl rings. The mol­ecules in polymorph I stack forming continuous columns along both the crystallographic [100] direction, with P⋯P distances of ca 6.55 Å (Fig. 3), and along the [010] direction, with an equivalent distance of ca 5.99 Å (the lengths of the respective axes). The rings exhibit similar angles to their respective directions, ca 57° in [100] and ca 52° in [010].

Figure 3 The structure of polymorph I, viewed along the [100] direction. Only one orientation of the H atoms bound to phospho­rus is shown and the rest have been omitted for clarity.

The distance between the mol­ecules along the columns appears to preclude direct π–π inter­actions (Avashti et al., 2014; Brunner et al., 2014). In fact, there do not appear to be any salient inter­molecular inter­actions observed in polymorph I. This suggests that the mol­ecules are arranged in such a way as to minimize repulsive contacts rather than form attractive inter­actions. As a result, all the duryl rings in this structure are orientated coplanar to either the [110] or [10] directions. The orientation of the rings in these directions, with methyl groups directed towards each other in the same plane, further hinders the close approach of the mol­ecules in the structure (Fig. 4).

Figure 4 The structure of polymorph I, viewed approximately along the [10] direction, showing the direct alignment of the methyl groups hindering close approach of the mol­ecules in this direction. H atoms have been omitted for clarity.

The packing in the structure of polymorph II is markedly different to that in polymorph I and much of this can be attributed to the fact that the two aryl rings are crystallographically independent in polymorph II. The mol­ecules align along the [010] direction, but the angles of the rings to this direction are shallower than in polymorph I; ca 28° for one and 0° for the other, where, once again, the methyl groups prevent the close approach of the π systems. Though the arrangement of the rings in the (02) plane, propagating along [010], is reminiscent of a similar arrangement in polymorph I, also in the [010] direction, in polymorph II the spacing between the mol­ecules in this direction is over 2 Å longer, with a P⋯P distance of ca 8.85 Å along [010], likely the result of the shallower P—C—P angle.

In contrast to the structure of polymorph I, there do appear to be some weak inter­molecular inter­actions in the structure of polymorph II in the form of C—H⋯C contacts between methyl groups and the aromatic rings. Two such contacts, with C⋯C distances < 3.7 Å, are observed (Table 3), which can be classified as weak Me⋯π inter­actions (Brunner et al., 2014). The two contacts form a ring motif between two of the duryl rings and propagate along the [010] direction, forming a chain of inter­molecular inter­actions, with each mol­ecule related to the next by the symmetry of the 2₁ screw axis (Fig. 5).

Table 3
Inter­molecular Me⋯π inter­actions (Å, °) in the structure of polymorph

D—H⋯A	D⋯A	H⋯A	D—H⋯A
C18—H18A⋯C15^i	3.694 (4)	2.83 (2)	150 (1)
C19^i—H19B^i⋯C15	3.637 (4)	2.88 (2)	136.6 (9)
Symmetry code: (i) −x + 1, −y + 2, −z + 1.

Figure 5 (a) A view of the ring motif formed in polymorph II of Me⋯π inter­actions between two mol­ecules and (b) the continuous chain motif formed of these inter­actions in the [010] direction. Close contacts are depicted as dashed lines and H atoms, with the exception of those bound to phospho­rus and the methyl groups involved in inter­molecular inter­actions, have been omitted for clarity.

By way of com­parison, a similar relationship between the mol­ecules is observed in both the [100] and [010] directions in polymorph I; however, in this case, the C⋯C distances are at least 0.1 Å too long to be considered Me⋯π inter­actions. Given this, it is possible that the weak but nonetheless attractive inter­actions observed in polymorph II are the root of the shallower C—P—C angle observed in this structure com­pared to that of polymorph I.

Although there are no discernible close contacts between the chains of mol­ecules in polymorph II, they appear to pack to form 2D layers coplanar to [100] (Fig. 6). Again, there do not appear to be any significant structure-directing inter­actions between these layers and the closest centroid–centroid distances between pairs of duryl rings across the layer boundary are ca 4.2 Å. As a result, it can be inferred that these rings are orientated simply to minimize steric inter­actions.

Figure 6 A view of the packing in polymorph II, showing the layers coplanar with the crystallographic (100) plane. H atoms have been omitted for clarity.

4. Conclusion

Bis(2,3,5,6-tetra­methyl­phen­yl)phosphine is the first secondary phosphine known to exhibit polymorphism and is observed to form two different crystalline forms depending on the solvent of crystallization. As structures of these reactive com­pounds are somewhat rare in the literature, this study expands the sum of structural knowledge of secondary phosphines, as well as revealing aspects of their supra­molecular chemistry.

The mol­ecules in each crystal structure vary in terms of their conformation, with the degree of steric pressure on the P atom observed to vary depending on the packing environment. Though polymorph I crystallizes with columnar motifs in the [100] and [010] directions, and no significant structure-directing inter­molecular inter­actions, polymorph II forms a 2D layered structure with weak Me⋯π inter­actions, forming a chain motif along the [010] direction.

The study of polymorphism in a secondary phosphine raises some inter­esting points in terms of the solid-state structures of these mol­ecules. It should be noted that as the same mol­ecule exhibits drastically different values for Σ°P, a measure of the steric pressure on the P atom, that this is not an intrinsic mol­ecular property and can be affected by the packing environment. This demonstrates that caution should be exercised when drawing conclusions based on these values, especially in the context of solution-phase calculations.

Supporting information

Computing details

Bis(2,3,5,6-tetramethylphenyl)phosphine (kji190001_fa)

Crystal data

C20H27P	F(000) = 324
Mr = 298.38	Dx = 1.178 Mg m^−3
Monoclinic, P2/n	Cu Kα radiation, λ = 1.54184 Å
a = 6.5476 (2) Å	Cell parameters from 4245 reflections
b = 5.9910 (2) Å	θ = 4.1–66.4°
c = 21.5676 (6) Å	µ = 1.35 mm^−1
β = 96.020 (2)°	T = 150 K
V = 841.36 (4) Å^3	Block, colourless
Z = 2	0.24 × 0.08 × 0.06 mm

Data collection

Rigaku Xcalibur Gemini ultra diffractometer with an Atlas detector	1500 independent reflections
Radiation source: fine-focus sealed X-ray tube, Enhance Ultra (Cu) X-ray Source	1299 reflections with I > 2σ(I)
Mirror monochromator	Rint = 0.040
Detector resolution: 10.3968 pixels mm^-1	θmax = 66.9°, θmin = 4.1°
ω scans	h = −7→7
Absorption correction: analytical [CrysAlis PRO (Rigaku OD, 2015), based on expressions derived by Clark & Reid (1995)]	k = −7→7
Tmin = 0.696, Tmax = 0.866	l = −25→24
11409 measured reflections

Refinement

Refinement on F^2	Primary atom site location: dual
Least-squares matrix: full	Hydrogen site location: mixed
R[F^2 > 2σ(F^2)] = 0.039	H atoms treated by a mixture of independent and constrained refinement
wR(F^2) = 0.118	w = 1/[σ^2(Fo^2) + (0.0665P)^2 + 0.3189P] where P = (Fo^2 + 2Fc^2)/3
S = 1.06	(Δ/σ)max = 0.001
1500 reflections	Δρmax = 0.27 e Å^−3
103 parameters	Δρmin = −0.24 e Å^−3
0 restraints

Special details

Geometry. All esds (except the esd in the dihedral angle between two l.s. planes) are estimated using the full covariance matrix. The cell esds are taken into account individually in the estimation of esds in distances, angles and torsion angles; correlations between esds in cell parameters are only used when they are defined by crystal symmetry. An approximate (isotropic) treatment of cell esds is used for estimating esds involving l.s. planes.

Refinement. Single-crystal diffraction was carried out on a Rigaku Xcalibur Altlas Gemini ultra diffractometer using Cu Kα radiation (λ = 1.54184 Å). Data were collected at 150 K using an Oxford Cryosystems CryostreamPlus open-flow N₂ cooling device. Intensities were corrected for absorption using a multifaceted crystal model created by indexing the faces of the crystal for which data were collected (Clark & Reid, 1995). Cell refinement, data collection and data reduction were undertaken via the software CrysAlis PRO (Rigaku OD, 2024). Both structures were solved using SHELXT (Sheldrick, 2015) and refined by SHELXL (Sheldrick, 2008) using the OLEX2 interface (Dolomanov et al., 2009).

Fractional atomic coordinates and isotropic or equivalent isotropic displacement parameters (Ų)

	x	y	z	Uiso*/Ueq	Occ. (<1)
P1	0.7500	0.70011 (11)	0.7500	0.0370 (2)
H1	0.930 (8)	0.760 (8)	0.736 (2)	0.055*	0.5
C1	0.6681 (2)	0.5206 (3)	0.68230 (8)	0.0305 (4)
C2	0.4837 (3)	0.5804 (3)	0.64606 (8)	0.0334 (4)
C3	0.4182 (3)	0.4548 (3)	0.59272 (8)	0.0355 (4)
C4	0.5370 (3)	0.2772 (3)	0.57701 (8)	0.0382 (4)
H4	0.4904	0.1910	0.5413	0.046*
C5	0.7214 (3)	0.2184 (3)	0.61090 (8)	0.0345 (4)
C6	0.7905 (2)	0.3439 (3)	0.66413 (8)	0.0311 (4)
C7	0.3561 (3)	0.7772 (4)	0.66223 (10)	0.0461 (5)
H7A	0.2539	0.7281	0.6894	0.069*
H7B	0.2860	0.8413	0.6239	0.069*
H7C	0.4453	0.8903	0.6838	0.069*
C8	0.2213 (3)	0.5095 (4)	0.55258 (9)	0.0465 (5)
H8A	0.1051	0.4965	0.5775	0.070*
H8B	0.2028	0.4051	0.5175	0.070*
H8C	0.2284	0.6623	0.5367	0.070*
C9	0.8429 (3)	0.0249 (4)	0.58956 (9)	0.0461 (5)
H9A	0.7649	−0.0477	0.5539	0.069*
H9B	0.8689	−0.0828	0.6237	0.069*
H9C	0.9740	0.0791	0.5773	0.069*
C10	0.9941 (3)	0.2855 (3)	0.70003 (8)	0.0353 (4)
H10A	1.0520	0.4184	0.7218	0.053*
H10B	1.0888	0.2315	0.6711	0.053*
H10C	0.9734	0.1686	0.7305	0.053*

Atomic displacement parameters (Ų)

	U^11	U^22	U^33	U^12	U^13	U^23
P1	0.0399 (4)	0.0324 (4)	0.0362 (4)	0.000	−0.0071 (3)	0.000
C1	0.0282 (8)	0.0338 (9)	0.0288 (8)	−0.0022 (7)	−0.0002 (6)	0.0041 (7)
C2	0.0288 (8)	0.0381 (9)	0.0324 (9)	0.0010 (7)	−0.0003 (7)	0.0066 (7)
C3	0.0276 (8)	0.0485 (11)	0.0294 (9)	−0.0006 (8)	−0.0014 (7)	0.0091 (8)
C4	0.0366 (9)	0.0509 (11)	0.0259 (8)	−0.0027 (8)	−0.0024 (7)	−0.0018 (8)
C5	0.0335 (9)	0.0401 (10)	0.0295 (8)	0.0007 (7)	0.0011 (7)	0.0017 (7)
C6	0.0282 (8)	0.0355 (9)	0.0290 (8)	−0.0011 (7)	0.0004 (7)	0.0056 (7)
C7	0.0369 (10)	0.0486 (11)	0.0506 (11)	0.0103 (9)	−0.0063 (8)	0.0003 (9)
C8	0.0337 (9)	0.0683 (14)	0.0351 (10)	0.0034 (9)	−0.0070 (8)	0.0075 (9)
C9	0.0490 (11)	0.0484 (11)	0.0397 (10)	0.0083 (9)	−0.0010 (8)	−0.0068 (9)
C10	0.0298 (9)	0.0410 (10)	0.0340 (9)	0.0030 (7)	−0.0024 (7)	0.0025 (8)

Geometric parameters (Å, º)

P1—H1	1.29 (5)	C6—C10	1.510 (2)
P1—C1^i	1.8472 (17)	C7—H7A	0.9800
P1—C1	1.8471 (17)	C7—H7B	0.9800
C1—C2	1.414 (2)	C7—H7C	0.9800
C1—C6	1.408 (2)	C8—H8A	0.9800
C2—C3	1.404 (3)	C8—H8B	0.9800
C2—C7	1.507 (3)	C8—H8C	0.9800
C3—C4	1.381 (3)	C9—H9A	0.9800
C3—C8	1.512 (2)	C9—H9B	0.9800
C4—H4	0.9500	C9—H9C	0.9800
C4—C5	1.390 (3)	C10—H10A	0.9800
C5—C6	1.407 (3)	C10—H10B	0.9800
C5—C9	1.505 (3)	C10—H10C	0.9800
C1^i—P1—H1	98 (2)	C2—C7—H7C	109.5
C1—P1—H1	100 (2)	H7A—C7—H7B	109.5
C1—P1—C1^i	108.78 (11)	H7A—C7—H7C	109.5
C2—C1—P1	116.72 (13)	H7B—C7—H7C	109.5
C6—C1—P1	122.08 (12)	C3—C8—H8A	109.5
C6—C1—C2	120.98 (16)	C3—C8—H8B	109.5
C1—C2—C7	122.17 (16)	C3—C8—H8C	109.5
C3—C2—C1	119.14 (16)	H8A—C8—H8B	109.5
C3—C2—C7	118.68 (15)	H8A—C8—H8C	109.5
C2—C3—C8	121.47 (17)	H8B—C8—H8C	109.5
C4—C3—C2	118.86 (15)	C5—C9—H9A	109.5
C4—C3—C8	119.67 (17)	C5—C9—H9B	109.5
C3—C4—H4	118.4	C5—C9—H9C	109.5
C3—C4—C5	123.14 (17)	H9A—C9—H9B	109.5
C5—C4—H4	118.4	H9A—C9—H9C	109.5
C4—C5—C6	118.78 (17)	H9B—C9—H9C	109.5
C4—C5—C9	119.49 (17)	C6—C10—H10A	109.5
C6—C5—C9	121.73 (16)	C6—C10—H10B	109.5
C1—C6—C10	121.94 (15)	C6—C10—H10C	109.5
C5—C6—C1	119.01 (15)	H10A—C10—H10B	109.5
C5—C6—C10	119.05 (15)	H10A—C10—H10C	109.5
C2—C7—H7A	109.5	H10B—C10—H10C	109.5
C2—C7—H7B	109.5

Symmetry code: (i) −x+3/2, y, −z+3/2.

Bis(2,3,5,6-tetramethylphenyl)phosphine (kji190003_fa)

Crystal data

C20H27P	F(000) = 648
Mr = 298.38	Dx = 1.159 Mg m^−3
Monoclinic, P21/c	Cu Kα radiation, λ = 1.54184 Å
a = 12.8874 (6) Å	Cell parameters from 3351 reflections
b = 8.8455 (3) Å	θ = 5.8–66.7°
c = 15.4635 (7) Å	µ = 1.33 mm^−1
β = 104.108 (5)°	T = 150 K
V = 1709.61 (13) Å^3	Block, colourless
Z = 4	0.36 × 0.14 × 0.05 mm

Data collection

Rigaku Xcalibur Gemini ultra diffractometer with an Atlas detector	3021 independent reflections
Radiation source: fine-focus sealed X-ray tube, Enhance Ultra (Cu) X-ray Source	2424 reflections with I > 2σ(I)
Mirror monochromator	Rint = 0.039
Detector resolution: 10.3968 pixels mm^-1	θmax = 66.8°, θmin = 3.5°
ω scans	h = −15→15
Absorption correction: analytical [CrysAlis PRO (Rigaku OD, 2015), based on expressions derived by Clark & Reid (1995)]	k = −10→9
Tmin = 0.746, Tmax = 0.939	l = −18→18
12709 measured reflections

Refinement

Refinement on F^2	Primary atom site location: dual
Least-squares matrix: full	Hydrogen site location: mixed
R[F^2 > 2σ(F^2)] = 0.047	H atoms treated by a mixture of independent and constrained refinement
wR(F^2) = 0.135	w = 1/[σ^2(Fo^2) + (0.0698P)^2 + 0.7357P] where P = (Fo^2 + 2Fc^2)/3
S = 1.06	(Δ/σ)max = 0.001
3021 reflections	Δρmax = 0.43 e Å^−3
214 parameters	Δρmin = −0.35 e Å^−3
182 restraints

Special details

Geometry. All esds (except the esd in the dihedral angle between two l.s. planes) are estimated using the full covariance matrix. The cell esds are taken into account individually in the estimation of esds in distances, angles and torsion angles; correlations between esds in cell parameters are only used when they are defined by crystal symmetry. An approximate (isotropic) treatment of cell esds is used for estimating esds involving l.s. planes.

Refinement. The hydrogen atom bound to phosphorous in this structure has been modelled over two positions. The P-H bond lengths were constrained to be similar using the SADI card. To prevent the close contact of one of these disordered hydrogens with an adjacent methyl group, this methyl group was also modelled as disordered over two positions.

Single-crystal diffraction was carried out on a Rigaku Xcalibur Altlas Gemini ultra diffractometer using Cu Kα radiation (λ = 1.54184 Å). Data were collected at 150 K using an Oxford Cryosystems CryostreamPlus open-flow N₂ cooling device. Intensities were corrected for absorption using a multifaceted crystal model created by indexing the faces of the crystal for which data were collected (Clark & Reid, 1995). Cell refinement, data collection and data reduction were undertaken via the software CrysAlis PRO (Rigaku OD, 2024). Both structures were solved using SHELXT (Sheldrick, 2015) and refined by SHELXL (Sheldrick, 2008) using the OLEX2 interface (Dolomanov et al., 2009).

Fractional atomic coordinates and isotropic or equivalent isotropic displacement parameters (Ų)

	x	y	z	Uiso*/Ueq	Occ. (<1)
P1	0.75650 (5)	0.71204 (7)	0.50367 (4)	0.0411 (2)
H1A	0.822 (3)	0.827 (4)	0.527 (3)	0.049*	0.6323
H1B	0.745 (6)	0.639 (7)	0.574 (3)	0.049*	0.3677
C1	0.81783 (16)	0.5738 (2)	0.44111 (15)	0.0357 (5)
C2	0.82942 (16)	0.6093 (2)	0.35486 (15)	0.0353 (5)
C3	0.87100 (17)	0.4999 (3)	0.30694 (16)	0.0401 (5)
C4	0.90209 (18)	0.3610 (3)	0.34647 (17)	0.0431 (5)
H4	0.9272	0.2876	0.3136	0.052*
C5	0.89728 (17)	0.3273 (2)	0.43253 (17)	0.0407 (5)
C6	0.85536 (16)	0.4348 (2)	0.48175 (15)	0.0381 (5)
C7	0.80033 (19)	0.7628 (3)	0.31418 (16)	0.0422 (5)
H7A	0.7252	0.7802	0.3072	0.063*
H7B	0.8168	0.7672	0.2570	0.063*
H7C	0.8404	0.8389	0.3525	0.063*
C8	0.8851 (2)	0.5296 (3)	0.21425 (18)	0.0549 (6)
H8A	0.9130	0.4407	0.1924	0.082*
H8B	0.9340	0.6121	0.2161	0.082*
H8C	0.8172	0.5549	0.1753	0.082*
C9	0.93877 (19)	0.1764 (3)	0.47214 (19)	0.0504 (6)
H9A	0.8850	0.1278	0.4958	0.076*
H9B	1.0020	0.1917	0.5191	0.076*
H9C	0.9557	0.1139	0.4267	0.076*
C11	0.62051 (16)	0.7494 (2)	0.43286 (14)	0.0327 (4)
C12	0.55112 (17)	0.6284 (2)	0.39960 (14)	0.0339 (5)
C13	0.44829 (17)	0.6597 (2)	0.34621 (14)	0.0359 (5)
C14	0.41651 (17)	0.8083 (3)	0.32953 (14)	0.0373 (5)
H14	0.3488	0.8279	0.2935	0.045*
C15	0.48205 (17)	0.9295 (2)	0.36467 (14)	0.0346 (5)
C16	0.58531 (16)	0.9002 (2)	0.41712 (14)	0.0326 (5)
C17	0.58273 (19)	0.4660 (2)	0.42098 (17)	0.0423 (5)
H17A	0.5214	0.4094	0.4271	0.063*
H17B	0.6372	0.4615	0.4758	0.063*
H17C	0.6098	0.4237	0.3737	0.063*
C18	0.37332 (19)	0.5335 (3)	0.30559 (17)	0.0464 (6)
H18A	0.4081	0.4686	0.2716	0.070*
H18B	0.3099	0.5754	0.2672	0.070*
H18C	0.3543	0.4761	0.3521	0.070*
C19	0.44052 (19)	1.0886 (3)	0.34468 (17)	0.0435 (5)
H19A	0.3728	1.0857	0.3017	0.065*
H19B	0.4906	1.1461	0.3211	0.065*
H19C	0.4318	1.1352	0.3985	0.065*
C20	0.65494 (19)	1.0335 (2)	0.45548 (16)	0.0416 (5)
H20A	0.6931	1.0680	0.4131	0.062*
H20B	0.7051	1.0034	0.5094	0.062*
H20C	0.6108	1.1138	0.4683	0.062*
C10A	0.848 (2)	0.404 (3)	0.5765 (8)	0.047 (3)	0.6323
H10A	0.8322	0.4960	0.6033	0.071*	0.6323
H10B	0.9150	0.3641	0.6103	0.071*	0.6323
H10C	0.7923	0.3314	0.5758	0.071*	0.6323
C10B	0.859 (4)	0.384 (5)	0.5759 (14)	0.046 (5)	0.3677
H10D	0.8657	0.4701	0.6143	0.069*	0.3677
H10E	0.9192	0.3178	0.5965	0.069*	0.3677
H10F	0.7943	0.3302	0.5765	0.069*	0.3677

Atomic displacement parameters (Ų)

	U^11	U^22	U^33	U^12	U^13	U^23
P1	0.0397 (3)	0.0397 (3)	0.0411 (3)	0.0051 (2)	0.0046 (2)	−0.0048 (2)
C1	0.0302 (10)	0.0325 (10)	0.0424 (11)	0.0001 (8)	0.0050 (8)	0.0008 (9)
C2	0.0294 (10)	0.0320 (10)	0.0429 (11)	−0.0008 (8)	0.0059 (9)	0.0022 (8)
C3	0.0346 (11)	0.0386 (11)	0.0479 (12)	0.0009 (9)	0.0116 (9)	0.0002 (9)
C4	0.0384 (12)	0.0362 (12)	0.0566 (14)	0.0044 (10)	0.0152 (10)	−0.0037 (10)
C5	0.0288 (10)	0.0310 (11)	0.0616 (14)	0.0008 (9)	0.0094 (10)	0.0045 (10)
C6	0.0282 (10)	0.0361 (11)	0.0482 (12)	0.0017 (9)	0.0058 (9)	0.0075 (9)
C7	0.0409 (12)	0.0355 (11)	0.0496 (13)	0.0039 (9)	0.0097 (10)	0.0071 (9)
C8	0.0587 (15)	0.0579 (16)	0.0528 (15)	0.0046 (13)	0.0225 (12)	0.0012 (12)
C9	0.0368 (12)	0.0352 (12)	0.0777 (18)	0.0062 (10)	0.0114 (12)	0.0112 (11)
C11	0.0342 (10)	0.0293 (10)	0.0372 (11)	−0.0006 (8)	0.0135 (8)	−0.0039 (8)
C12	0.0363 (11)	0.0301 (10)	0.0394 (11)	−0.0027 (8)	0.0168 (9)	−0.0030 (8)
C13	0.0376 (11)	0.0352 (11)	0.0386 (11)	−0.0067 (9)	0.0162 (9)	−0.0068 (9)
C14	0.0314 (10)	0.0428 (12)	0.0391 (11)	−0.0008 (9)	0.0115 (9)	−0.0032 (9)
C15	0.0360 (11)	0.0326 (10)	0.0384 (11)	0.0015 (9)	0.0151 (9)	−0.0006 (8)
C16	0.0342 (10)	0.0296 (10)	0.0365 (11)	−0.0017 (8)	0.0132 (8)	−0.0024 (8)
C17	0.0445 (12)	0.0283 (11)	0.0571 (14)	−0.0024 (9)	0.0180 (11)	−0.0011 (10)
C18	0.0428 (13)	0.0443 (13)	0.0549 (14)	−0.0128 (10)	0.0172 (11)	−0.0139 (11)
C19	0.0429 (12)	0.0362 (12)	0.0532 (14)	0.0063 (10)	0.0152 (11)	0.0031 (10)
C20	0.0411 (12)	0.0293 (11)	0.0536 (14)	−0.0030 (9)	0.0102 (10)	−0.0043 (9)
C10A	0.043 (6)	0.042 (6)	0.053 (3)	0.013 (5)	0.006 (3)	0.017 (3)
C10B	0.045 (9)	0.045 (10)	0.050 (5)	0.019 (6)	0.016 (5)	0.009 (4)

Geometric parameters (Å, º)

P1—H1A	1.32 (4)	C12—C13	1.408 (3)
P1—H1B	1.31 (4)	C12—C17	1.508 (3)
P1—C1	1.852 (2)	C13—C14	1.382 (3)
P1—C11	1.856 (2)	C13—C18	1.510 (3)
C1—C2	1.413 (3)	C14—H14	0.9300
C1—C6	1.411 (3)	C14—C15	1.391 (3)
C2—C3	1.402 (3)	C15—C16	1.404 (3)
C2—C7	1.505 (3)	C15—C19	1.511 (3)
C3—C4	1.387 (3)	C16—C20	1.513 (3)
C3—C8	1.511 (3)	C17—H17A	0.9600
C4—H4	0.9300	C17—H17B	0.9600
C4—C5	1.380 (3)	C17—H17C	0.9600
C5—C6	1.406 (3)	C18—H18A	0.9600
C5—C9	1.511 (3)	C18—H18B	0.9600
C6—C10A	1.516 (8)	C18—H18C	0.9600
C6—C10B	1.514 (13)	C19—H19A	0.9600
C7—H7A	0.9600	C19—H19B	0.9600
C7—H7B	0.9600	C19—H19C	0.9600
C7—H7C	0.9600	C20—H20A	0.9600
C8—H8A	0.9600	C20—H20B	0.9600
C8—H8B	0.9600	C20—H20C	0.9600
C8—H8C	0.9600	C10A—H10A	0.9600
C9—H9A	0.9600	C10A—H10B	0.9600
C9—H9B	0.9600	C10A—H10C	0.9600
C9—H9C	0.9600	C10B—H10D	0.9600
C11—C12	1.409 (3)	C10B—H10E	0.9600
C11—C16	1.411 (3)	C10B—H10F	0.9600
C1—P1—H1A	109.1 (18)	C12—C13—C18	120.9 (2)
C1—P1—H1B	105 (3)	C14—C13—C12	119.39 (19)
C1—P1—C11	105.74 (9)	C14—C13—C18	119.7 (2)
C11—P1—H1A	118.4 (18)	C13—C14—H14	118.8
C11—P1—H1B	108 (3)	C13—C14—C15	122.4 (2)
C2—C1—P1	120.22 (16)	C15—C14—H14	118.8
C6—C1—P1	119.09 (17)	C14—C15—C16	118.89 (19)
C6—C1—C2	120.7 (2)	C14—C15—C19	119.2 (2)
C1—C2—C7	121.5 (2)	C16—C15—C19	121.96 (19)
C3—C2—C1	119.18 (19)	C11—C16—C20	122.31 (19)
C3—C2—C7	119.3 (2)	C15—C16—C11	119.61 (19)
C2—C3—C8	122.1 (2)	C15—C16—C20	118.08 (18)
C4—C3—C2	119.0 (2)	C12—C17—H17A	109.5
C4—C3—C8	118.9 (2)	C12—C17—H17B	109.5
C3—C4—H4	118.6	C12—C17—H17C	109.5
C5—C4—C3	122.7 (2)	H17A—C17—H17B	109.5
C5—C4—H4	118.6	H17A—C17—H17C	109.5
C4—C5—C6	119.3 (2)	H17B—C17—H17C	109.5
C4—C5—C9	119.2 (2)	C13—C18—H18A	109.5
C6—C5—C9	121.5 (2)	C13—C18—H18B	109.5
C1—C6—C10A	119.5 (9)	C13—C18—H18C	109.5
C1—C6—C10B	128.0 (15)	H18A—C18—H18B	109.5
C5—C6—C1	118.9 (2)	H18A—C18—H18C	109.5
C5—C6—C10A	121.5 (9)	H18B—C18—H18C	109.5
C5—C6—C10B	113.1 (15)	C15—C19—H19A	109.5
C2—C7—H7A	109.5	C15—C19—H19B	109.5
C2—C7—H7B	109.5	C15—C19—H19C	109.5
C2—C7—H7C	109.5	H19A—C19—H19B	109.5
H7A—C7—H7B	109.5	H19A—C19—H19C	109.5
H7A—C7—H7C	109.5	H19B—C19—H19C	109.5
H7B—C7—H7C	109.5	C16—C20—H20A	109.5
C3—C8—H8A	109.5	C16—C20—H20B	109.5
C3—C8—H8B	109.5	C16—C20—H20C	109.5
C3—C8—H8C	109.5	H20A—C20—H20B	109.5
H8A—C8—H8B	109.5	H20A—C20—H20C	109.5
H8A—C8—H8C	109.5	H20B—C20—H20C	109.5
H8B—C8—H8C	109.5	C6—C10A—H10A	109.5
C5—C9—H9A	109.5	C6—C10A—H10B	109.5
C5—C9—H9B	109.5	C6—C10A—H10C	109.5
C5—C9—H9C	109.5	H10A—C10A—H10B	109.5
H9A—C9—H9B	109.5	H10A—C10A—H10C	109.5
H9A—C9—H9C	109.5	H10B—C10A—H10C	109.5
H9B—C9—H9C	109.5	C6—C10B—H10D	109.5
C12—C11—P1	120.29 (16)	C6—C10B—H10E	109.5
C12—C11—C16	120.43 (19)	C6—C10B—H10F	109.5
C16—C11—P1	119.18 (15)	H10D—C10B—H10E	109.5
C11—C12—C17	122.0 (2)	H10D—C10B—H10F	109.5
C13—C12—C11	119.16 (19)	H10E—C10B—H10F	109.5
C13—C12—C17	118.81 (19)