Figure 1
The overall organization of the ceruloplasmin molecule, showing the six cupredoxin domains (domains 1, 2, 3, 4, 5 and 6 in red, orange, yellow, green, blue and purple, respectively) and the locations of the metal-binding sites: Cu2+ as blue spheres, Ca2+ as an olive-green sphere and Na+ as red spheres. The relatively planar bottom surface and the protuberances at the top surface are clearly visible. The figures were prepared with the PyMOL program (DeLano, 2002). |