Figure 3
Ribbon representation showing two molecules of PhoB (green) in complex with DNA shown in space-filling representation (Blanco et al., 2002; PDB code 1gxp
). VicRc is shown in red, superimposed onto one PhoB monomer. The consensus sequences for YycF/VicR homologues and PhoB targets are also shown, with the C to A/T substitution mentioned in the text indicated by red arrows in each repeat. The filled red arrow indicates the corresponding base pair in the model, which has been coloured magenta and lies close to the recognition helix. The loop region of PhoB does not reach the DNA, while the VicRc loop could make contact with it. |