 | Acta Crystallographica Section D Acta Crystallographica Section D BIOLOGICAL CRYSTALLOGRAPHY |
journal menu
![[Figure 1]](hm5093fig1mag.jpg)
|
|
Figure 1
Residues at position 1 of CsA and the ISA247 stereoisomers. Structural formulae are displayed for (a) the cyclosporin residue MeBmt1, (b) the E-ISA247 residue E-MePmt1 and (c) the Z-ISA247 residue Z-MePmt 1. 2Fo − Fc electron-density maps around (d) E-MePmt1 and (e) Z-MePmt1 contoured at one standard deviation above the mean density are displayed in green. Surface and ball-and-stick representations of the crystal structures of CypA in grey complexed with (f) CsA (PDB entry 2rma ; Ke et al., 1994  ), (g) E-ISA247 and (h) Z-ISA247 in yellow are shown. The distances between the Ala103 backbone carbonyl of CypA and residue 1 of the cyclic peptides are marked by black arrows. |
![[Figure 1]](hm5093fig1.jpg)
| BIOLOGICAL CRYSTALLOGRAPHY |
ISSN: 1399-0047
