Figure 3
Superposition of the ternary Cn–CypA–CsA complex with the binary CypA–ISA247 complexes. Cn, CypA and the CsA residue MeBmt1 of the ternary complex (PDB entry 1m63
; Huai et al., 2002) are displayed in yellow, grey and pink, respectively. The MePmt1 residues of E-ISA247 and Z-ISA247 are shown in green and cyan, respectively. A close contact between E-ISA247 and Cn (carbon-to-nitrogen distance of 2.4 Å) is marked by a black arrow. |