Structural insights into lipid-dependent reversible dimerization of human GLTP

Samygina, V.R.; Ochoa-Lizarralde, B.; Popov, A.N.; Cabo-Bilbao, A.; Goni-de-Cerio, F.; Molotkovsky, J.G.; Patel, D.J.; Brown, R.E.; Malinina, L.

doi:10.1107/S0907444913000024

Acta Crystallographica Section D
Acta Crystallographica
Section D BIOLOGICAL CRYSTALLOGRAPHY

IUCr IT WDC

home archive editors for authors for readers submit subscribe open access

view article

Figure 4
Conformational adaptability of disulfatide headgroups. (a) Superimposed ligand conformations in open and closed dimers (crystal forms 1 and 2, respectively) of wtGLTP. Protein moieties were superposed and skipped. Disulfatide molecules are shown in stick representation; colour codes for O, N and S atoms are red, blue and green, respectively. C atoms are coloured magenta for crystal form 1 and pink for crystal form 2. (b) Disulfatide conformations in two crystal forms (1 and 4; Tables 1

and 2

) of D48V. C atoms are coloured cyan for crystal form 1 and light cyan for crystal form 4. Colour codes for other atoms are as in (a). (c, d) Disulfatide in the open dimer of wtGLTP versus the two conformations of disulfatide shown in (b).

BIOLOGICAL
CRYSTALLOGRAPHY

ISSN: 1399-0047

Volume 69| Part 4| March 2013| Pages 603-616

doi:10.1107/S0907444913000024

Follow Acta Cryst. D

Search term		doi		Advanced search
Author		volume	page