Figure 8
Superimposition of two distinct protein-bound CoA conformations. (a) Stick representation of M31G RipA with the catalytic glutamate shown in magenta and the CoA shown in white with the superimposed A. aceti SCACT (PDB entry 4eu6; Mullins & Kappock, 2012 ) and C. aminobutyricum 4-HBCoAT (PDB entry 3qdq; Macieira et al., 2012 ) CoAs shown in gray and wheat, respectively. (b) Stick representation of F60M RipA with the catalytic glutamate shown in teal and the CoA shown in white with the superimposed M. tuberculosis malate synthase G (PDB entry 2gq3; Anstrom & Remington, 2006 ) and M. tuberculosis FadB (PDB entry 4b3i; Venkatesan & Wierenga, 2013 ) CoAs shown in gray and wheat, respectively. O, N, S and P atoms are colored red, blue, yellow and orange, respectively. |