Figure 6
Assembly pathway for the `Z' dPhTET2 6s:hPhTET3 6s heterododecamer (peak 1): the observation of a specific internal hexamer–hexamer topology by SANS, together with the exclusion of alternative topologies, points to a specific assembly pathway involving intertwined heterohexamers. Thick continuous and thin broken arrows represent strong and weak pathways for the dynamic equilibrium between respective states. An alternative assembly mode is presented in Supplementary Fig. S8. |