Figure 2
Overview of mouse P-gp at 3.4 Å resolution. Magnified insets at different orientations are shown with the resulting 2mFo − DFc electron density (where m is the figure of merit and D is the σA weighting factor) contoured at 1σ; individual transmembrane helices are shown in different colors. TM1 is in red, TM2 is in orange, TM3 is in yellow, TM4 is in light green, TM5 is in sky blue, TM6 is in pink, TM7 is in dark brown, TM8 is in olive, TM9 is in light brown, TM10 is in forest, TM11 is in dark blue and TM12 in deep purple. |