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Figure 4
Key P-gp residues involved in binding homotrimeric cyclopeptides. Stereoviews of the binding pocket are shown perpendicular to the membrane and viewed from the cytosol. P-gp residues are shown as sticks, with those involved in binding subset A ligands colored yellow and those involved in binding subset B ligands colored magenta. The ligand coloring is consistent with that shown in Fig. 3[link]; QZ-Ala, green; QZ-Val, blue; QZ-Leu, yellow; QZ-Phe, red.

Journal logoBIOLOGICAL
CRYSTALLOGRAPHY
ISSN: 1399-0047
Volume 71| Part 3| February 2015| Pages 732-741
doi:10.1107/S1399004715000978
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