Figure 7
The interaction site near Trp63. (a)–(c) depict the results from the current work with different additives: (a) (R)-MPD; (b) (S)-MPD; (c) (RS)-MPD. The red spheres in (b) are the O atoms of water molecules. For comparison, the results of Michaux et al. (2008), which used (RS)-MPD, are also presented (d). The 2Fo − Fc density is shown as a gray mesh contoured at 1.5σ, except for the (S)-MPD molecule in (d), which is shown at 1.0σ. This is to highlight that C4 (denoted by an arrow) protrudes from the density. |