Structural characterization of substrate and inhibitor binding to farnesyl pyrophosphate synthase from Pseudomonas aeruginosa

Schmidberger, J.W.; Schnell, R.; Schneider, G.

doi:10.1107/S1399004715001121

Acta Crystallographica Section D
Acta Crystallographica
Section D BIOLOGICAL CRYSTALLOGRAPHY

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Figure 2
The inhibitory effect of zoledronate (a) and ibandronate (b) on farnesyl pyrophosphate synthase from P. aeruginosa. The dose-response curves resulted in IC₅₀ values of 15.2 nM and 2.7 µM, respectively.

BIOLOGICAL
CRYSTALLOGRAPHY

ISSN: 1399-0047

Volume 71| Part 3| February 2015| Pages 721-731

doi:10.1107/S1399004715001121

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