Figure 6
Superimposition of monomeric Tah1 structures. (a) Tah1 monomeric structures are superimposed. Magenta represents Tah1 from the structure of the Tah1–Pih complex (PDB entry 4cgu; Pal et al., 2014), while green and cyan are solution structures (PDB entries 2lsu and 2lsv, respectively; Back et al., 2013). Helices 5 and 4 are labelled. The tubes in magenta and cyan represent the bound Hsp90 peptide. (b) Crystallographic interface between the loop connecting α-helices 4 and 5 and an adjacent Tah1 monomer. Yellow and green represent the two halves of a Tah1 dimer in contact with an adjacent Tah1 molecule (shown in cyan). Hydrogen bonds are shown as dotted blue lines, while water molecules are shown as red spheres. |