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Figure 2
The two near-symmetric box A domains collaborate to bend DNA. (a) View of both domains enclosing the kinked DNA. The HMGB1 box A domains are colored purple and cyan, whereas the kinked DNA is colored orange. Phe37 of both domains is indicated. (b) View showing the 2° intercalation site, with the two phenylalanines at the central CG base pair. (c) Surface representation of the two box A domains. (d) Surface representation of the DNA showing the pocket enclosing the two Phe37 residues (indicated by arrows).

Journal logoBIOLOGICAL
ISSN: 1399-0047
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