|
Figure 3
The kinked DNA structure. (a) DNA–box A contacts (NUCPLOT). Hydrogen bonds are shown as solid lines and nonbound contacts are shown as dashed lines. (b) Close-up views of the protein–DNA purine base interactions. Hydrogen bonds from residues Phe37 and Ser41 to base pairs A7 and G6 and a water-mediated hydrogen bond from Ser13 to A9 are shown in the upper and lower diagrams, respectively. (c) Comparison of DNA parameters for HMG-box intercalation sites. The roll and twist angles for box A in this structure were obtained with 3DNA, and those for PDB entries 1ckt (box A, cisplatin; Ohndorf et al., 1999 ![]() ![]() ![]() ![]() ![]() |