Figure 4
C. perfringens sortase D is distinct from the class D enzyme isolated from B. anthracis. (a) Superposition of the C. perfringens (blue; PDB entry 4d70
) and B. anthracis (gold; PDB entry 2ln7
) sortase D structures. (b) Comparison of the distinctive loops revealing the presence of a two-turn α-helix within the C. perfringens sortase D (orange) β2–β3 loop that is not present in the B. anthracis SrtD loop (green). The β2–β3 and β4–H1 loops are found to be disordered in the PDB structure 2ln7
but well ordered in the C. perfringens sortase D structure. Figures were generated using PyMOL. |