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Figure 3
Structural superposition of TkA with the E. coli type I L-asparaginase. The structures are in approximately the same orientation as that shown in Fig. 2[link]. Chains A and B of TkA and both subunits of the E. coli enzyme (PDB entry 2p2d) are coloured red, yellow and blue, respectively. The arrows indicate the segments which adopt different conformations in response to substrate binding.

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
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