Experimental data and complementary prior knowledge versus resolution. The grey arrow shows resolution in Å and the grey bar above it indicates the level of macromolecular structural detail that can be observed in the corresponding resolution range. The blue panel shows experimental methods that deliver information in the corresponding resolution range; the NMR bar is coloured with a pattern to reflect the different nature of NMR-derived data (distances between points rather than a continuous distribution of density). The green panel shows structural restraints that are useful for complementing the experimental data that are missing at certain resolutions. The top arrow indicates the minimal theoretical resolvability of peaks in the absence of noise at a given resolution.