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![[Figure 2]](ic5104fig2_combined_mag.jpg)
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Figure 2
Effect of hole size on thin films and particle distributions. (a) A lacey grid with an irregular distribution of hole sizes and shapes. (b) A Quantifoil R1.2/1.3 with a regular distribution of evenly sized holes. (c) An even distribution of ice across the hole as seen for the R1.2/1.3 grids. (d) An example of broken substrate in the hole centre. (e) Thin ice in the centre of the hole excluding the virus and causing it to clump towards the edge of the hole. (f) Virus particles forming a semi-ordered array in the area of thin ice. (g) An example of a 750 kDa multiprotein complex disassociating in the large holes of lacey carbon. (h) The same multiprotein complex remains intact and with a range of angular distributions in the smaller holes of lacey carbon. Scale bars: (a), (b) 2 µm; (c), (d), (f) 200 nm; (e) 100 nm; (g), (h) 50 nm. |
![[Figure 2]](ic5104fig2_combined.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
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