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Figure 7
Diversity of MT ultrastructure in neurons. (a) A range of particle sizes and distributions are seen in the lumen of neuronal MTs. (b) The majority (24/25) of neuronal MT ends have relatively short flared regions similar to those observed in GMPCPP-stabilized MTs (Fig. 2[link]a), while only one example of a longer curved sheet extension was seen and no highly curved ends associated with in vitro depolymerizing MTs (Fig. 5[link]a) were observed. (c) Three examples of lattice defects observed in neuronal MTs. In each case, a section through the tomogram is depicted on the left and a surface rendering of the MT wall is shown on the right.

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
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