Figure 4
The intermediates in the reaction of haem peroxidases. The structures determined by NPX are circled. (a) The ferric (resting) enzyme from cytochrome c peroxidase, (b) compound I of cytochrome c peroxidase, (c) compound II of ascorbate peroxidase. The radicals on the porphyrin in the case of ascorbate peroxidase and on a tryptophan residue in the case of cytochrome c peroxidase are shown as and , respectively. The red crosses show alternative structures eliminated by NPX. |