Figure 2
SAXS analysis of the MERS-CoV CTD. (a) Guinier plot for all concentrations showing the absence of aggregation. (b) GNOM fit of the merged profile. (c) Distance distribution P(r) of the merged data. (d) CRYSOL fit of the model (PDB entry 6g13) with the experimental data (blue line) and CRYSOL fit of an enhanced model featuring the disordered N-terminal region residues modeled by EOM (red line). The three corresponding enhanced models calculated by EOM are shown also in the inset in (d). |