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![[Figure 5]](cb5118fig5mag.jpg)
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Figure 5
Comparison of lactose binding to BgaR and arabinose binding to AraC. The left image shows a comparison of the AraC structure with arabinose bound with the BgaR structure with lactose bound, showing that the overall folds are quite similar between the proteins and that the binding sites are both found between the β-sheets of the jelly roll; the AraC structure is in yellow and the BgaR structure is in green. The middle and right images are enlarged perspectives of the left image to show in detail how the arabinose sits at almost 90° in the pocket compared with the lactose moiety. The N-terminus of AraC does not participate in the β-sheets formed but instead comes up to enclose the binding site for the saccharide, unlike the BgaR structure. The N-terminus is labelled in each case. |
![[Figure 5]](cb5118fig5.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
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