Figure 1
Crystal structure comparisons at the saccharide-binding site of concanavalin A at (a) room temperature (PDB entry 1scs; Emmerich et al., 1994) compared with cryo-temperature (PDB entry 1nls; Deacon et al., 1997). (b) The same view as (a) for the glucoside-bound room-temperature crystal structure (PDB entry 1gic; Bradbrook et al., 1998). (c) The view in (b) superimposed on the view in (a), for which some side-chain adjustments to the glucoside binding and displacement of bound waters are evident and as expected. |