Figure 9
Graphs showing identity versus the LLG score for the different hypotheses generated by SEQUENCE SLIDER (SLIDER) for PDB entry 5lcy. The scale difference is owing to each cycle building upon the previous model. (a) First SEQUENCE SLIDER cycle, whereby the correct sequence assignment is distinguished for chains A, B, C and D, shown in magenta, orange, yellow and red, respectively. (b) The correct sequence is assigned for the NCS-related chains E+F+G+H. (c) The correct sequence is assigned for the NCS-related chains E+F+G+H. SEQUENCE SLIDER models and models with random sequence are represented by circles and crosses, respectively. |