Figure 8
Solution of NovP with ARCIMBOLDO_BORGES. (a) Cartoon representation of the model, with PDB entry 1vid (grey) providing the template (turquoise) for library generation. (b) A model extracted from PDB entry 2gdz located by Phaser is shown in yellow and the final deposited structure of NovP (PDB entry 2wk1) is shown as a transparent red cartoon. (c) Detail of residue 119A: Fo FOM-weighted map at 3σ showing clear electron density for the side chain of a tryptophan after performing density modification and autotracing with SHELXE. |