Figure 1
Structure of hENPP1 with AMP and comparison with mouse ENPP1 (PDB entry 4b56). (a) The SMB domain is at the N-terminus and is shown with red helices, the catalytic domain is shown with cyan helices and magenta β-strands with AMP represented as spheres, and the nuclease-like domain is at the top of the figure and is shown with red helices and yellow β-strands. (b) The image is rotated approximately 90° clockwise and mouse ENPP1 (PDB entry 4b56) is superposed on the human structure. The mouse structure is coloured monochrome wheat with the N- and C-termini labelled. This figure was generated using PyMOL and GIMP. |