Figure 1
Flowchart of a model-sequence validation procedure. The dashed box in (a) encloses the initial steps of reference-sequence identification for each protein chain in the input model. If a reference sequence can be identified, the chain is divided into continuous test fragments that are systematically assigned to the reference sequence (b). The method reports possible issues (red boxes) if a reference sequence cannot be identified or if a sequence assigned to a test fragment with high confidence (p-value below the threshold) does not match the input model. |