Crystal structures of the molecular class A β-lactamase TEM-171 and its complexes with tazobactam

Grigorenko, V.G.; Petrova, T.E.; Carolan, C.; Rubtsova, M.Y.; Uporov, I.V.; Pereira, J.; Chojnowski, G.; Samygina, V.R.; Lamzin, V.S.; Egorov, A.M.

doi:10.1107/S2059798322004879

Acta Crystallographica Section D
Acta Crystallographica
Section D STRUCTURAL BIOLOGY

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Figure 4
Cartoon representation of loop 213–218 in TEM-171 and other class A β-lactamases. (a) Superposition of TEM-171 complex II (magenta), TEM-171 (light blue) and TEM-65 (blue). (b) Superposition of TEM-171 complex II with PDB entries 1li0 (orange), 1m40 (or 1jvj, 1nxy, 1ny0 and 1nym; blue), complex I (blue-green) and TEM-171 (pale green). A K⁺ ion in PDB entry 1l10 is shown as a light blue sphere; the K⁺ ion in PDB entries 1m40, 1jvj, 1nxy, 1ny0 and 1nym is shown as an orange sphere. Tazobactam in complex II is shown in stick representation.

STRUCTURAL
BIOLOGY

ISSN: 2059-7983

Volume 78| Part 7| July 2022| Pages 825-834

https://doi.org/10.1107/S2059798322004879

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