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![[Figure 10]](qe5007fig10mag.jpg)
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Figure 10
Results output from a Slice'N'Dice job. (a) PDB entry 8gtd chains A (a) and B (b) were generated using ColabFold (Mirdita et al., 2022  ). Cyan models represent the unsplit ColabFold models. Both were split into two slices using BIRCH clustering, which is the default in Slice'N'Dice. The colouring to represent each cluster is shown in (e). The slice on chain A segmented the model suitably; however, chain B was not segmented into domains as clearly, although this did not significantly impact the overall results. Slice'N'Dice run alongside the input map file EMDB entry EMD-34250 (c) managed to place 45 out of 48 placements into the correct locations (d). However, one false positive passed the classifier check (e) and was placed in the head-to-tail joining protein instead in the portal protein. Utilizing the probability scores generated by the pipeline, it is evident that the placement has a lower score (∼0.52) than its nearest counterpart (∼0.78) and should be treated as a less confident result by the end user. The probability score is between 0 and 1. |
![[Figure 10]](qe5007fig10.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
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