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Figure 5
(a) The closest match in the PDB to the target structure, PDB entry 1f0l (orange, r.m.s.d. 5.74 Å), superimposed on the crystal structure of PDB entry 7rb4 (grey). (b) An AlphaFold2 model of the target coloured on a scale of orange to blue, where orange indicates a low pLDDT score (≤50) and blue indicates a high pLDDT score (≥90), superimposed (r.m.s.d. 3.19 Å) on the crystal structure of PDB entry 7rb4 (grey). (c) The AlphaFold2 model after preprocessing, slicing and MR with Slice'N'Dice (green, r.m.s.d. 0.32 Å), shown against the crystal structure of PDB entry 7rb4 (grey). (d) The placed AlphaFold2 model after 20 cycles of model building with Buccaneer (red, r.m.s.d. 0.14 Å, global mapCC 0.84) shown against the crystal structure of PDB entry 7rb4 (grey). This figure was made using Moorhen. |