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![[Figure 8]](ud5057fig8mag.jpg)
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Figure 8
Kleywegt plots comparing the backbone dihedral angles (Φ, Ψ) for the linker region connecting the 1B and RecA1 domains across structures of NSP13. The plots compare the myricetin-bound SARS-CoV-2 NSP13 crystal structure (PDB entry 9i1s, chain B) with the crystal structures of (a) unliganded SARS-CoV-2 NSP13 (PDB entry 9i4v, chain B), (b) SARS-CoV-1 NSP13 (PDB entry 6jyt, chain B) and (c) AMP-PNP-bound SARS-CoV-2 NSP13 (PDB entry 7nn0, chain A), as well as (d) the RNA-bound cryo-EM structure of SARS-CoV-2 NSP13 (PDB entry 7rdy, chain E). Dashed lines connect corresponding residues in each model, highlighting positional shifts, while contour lines indicate favoured and allowed regions in the multiple-model Ramachandran plot. |
![[Figure 8]](ud5057fig8.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
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