journal menu
![[Figure 3]](ag5054fig3_combined_mag.jpg)
|
|
Figure 3
Ensemble modelling of SFPQ using EOM: a potential N–C-terminal interaction. (a) SEC-SAXS scattering data of full-length SFPQ shown as log(I) versus log(q). The fit of the EOM ensemble is shown as a black line. The χ2 of 1.04 indicates an excellent fit to the data. (b) Normalized residual plot of the EOM fit to experimental data: the lack of systematic variation is indicative of a good fit. (c) Frequency versus Rg plot of the initial random starting pool and the ensembles that fit the data. (d) Frequency versus Dmax plot of the initial random starting pool and selected ensembles that fit the data. (e) Atomistic models of full-length SFPQ which are from the ensemble that fit the data. (f) SEC-SAXS scattering data of SFPQ1–598 as a log(I) versus log(q) plot. The fit of the EOM ensemble is shown as a red line. A χ2 of 1.012 indicates an excellent fit to the data. (g) Normalized residual plot of the EOM fit to the experimental data: the lack of systematic variation is indicative of a good fit. (h) Frequency versus Rg plot of the initial random pool and selected ensembles which fit the data. (i) Frequency versus Dmax plot of initial random pools and selected ensembles for SFPQ1–598. (j) Selection of models from the ensemble that fit the SFPQ1–598 data. |
![[Figure 3]](ag5054fig3_combined.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
access
