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![[Figure 1]](bar5001fig1mag.jpg)
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Figure 1
The condition number κ(H) for nearest-neighbor interpolation and no CTF. (a) Lower bound (blue, solid) and average value (red, dashed) of κ(H) for N = 10 000 images, Fourier radius of R voxels in the range {1, 16, 32, 48, 64, …, 304} and λ = 10−8. The lower bound is computed using equation (21) ![[link]](../../../../../../logos/arrows/d_arr.gif){kind=small} , where p(R) is computed empirically using spherical and circular shells of radius R. To compute the average value of κ(H) for each R, ten sets of N uniformly distributed orientations are generated and the average condition number is plotted, as well as error bars showing the minimum and maximum values of the condition number for these sets of orientations. (b, c) The z = 0 plane of the diagonal of the nearest-neighbor Hessian matrix H reshaped as a 3D volume for N = 5 and N = 100 images, respectively, and grid size 256. |
![[Figure 1]](bar5001fig1.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
