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Figure 4
(a) Superposition of the Abl SH3 domain (PDB entry 5oaz, blue) and Abl-based chimeric constructions represented as cartoons: Abl_Src-2 (PDB entry 7pvr), Abl_Src-RT (PDB entry 7pw2) and Abl_Src-nSrc (PDB entry 7pvv). (b, c, d) Hydrogen-bond networks in the n-Src loop of (b) Abl_Src-2 (PDB entry 7pvr), (c) Abl_Src-RT (PDB entry 7pw2) and (d) Abl_Src-nSrc (PDB entry 7pvv). |
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