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Figure 6
pLDDT distibutions for the major low-pLDDT prediction modes, with pLDDT bins of 1, for sequences from the human proteome. Barbed wire (red, triangles) correlates with lower pLDDT scores. Near-predictive (green, circles) correlates with higher pLDDT scores. The crossing point for barbed wire and near-predictive is close to 50; the yellow/orange boundary in conventional pLDDT coloring. If not for pseudostructure (gold, squares), which correlates only weakly with low pLDDT, a pLDDT 50 cutoff would be sufficient to select for most near-predictive. |
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