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![[Figure 7]](nz5018fig7mag.jpg)
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Figure 7
Relationships of AlphaFold2 prediction modes with MobiDB disorder annotations. From left to right: prediction-disorder-iupl shows a typical distribution for many predictions of disorder (see supporting information), where high-pLDDT residues are least associated with disorder and barbed wire residues are most associated, but no mode stands out as exceptional. The distributions to the right are exceptions to this general pattern. Low-complexity sequences are about equally associated with both pseudostructure and barbed wire. Proline-rich sequences are preferentially associated with pseudostructure, where we observe the polyproline II conformation. Disorder-to-disorder binding somewhat favors pseudostructure. Disorder-to-order binding somewhat favors near-predictive. Predicted signal peptides strongly favor pseudostructure over any other mode. |
![[Figure 7]](nz5018fig7.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
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