How many (distinguishable) classes can we identify in single-particle analysis?

Lauzirika, O.; Pernica, M.; Herreros, D.; Ramírez-Aportela, E.; Krieger, J.; Gragera, M.; Iceta, M.; Conesa, P.; Fonseca, Y.; Jiménez, J.; Filipovic, J.; Carazo, J.M.; Sorzano, C.O.S.

doi:10.1107/S2059798325007831

Acta Crystallographica Section D
Acta Crystallographica
Section D STRUCTURAL BIOLOGY

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Figure 6
Top left: ChimeraX visualization of the 49 classes detected in the EMPIAR-10391 data set. Top right: StructMap representation of the 49 classes in a two-dimensional projection (the brightness corresponds to multiple classes projecting onto the same coordinate). Middle: dendrogram representation of the hierarchical clustering of the maps using complete linkage. Bottom: purity of each of the 49 calculated classes in terms of the original classification deposited in EMPIAR.

STRUCTURAL
BIOLOGY

ISSN: 2059-7983

Volume 81| Part 10| October 2025| Pages 535-544

https://doi.org/10.1107/S2059798325007831

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