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![[Figure 5]](chr5009fig5mag.jpg)
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Figure 5
Structure and lattice interactions of a `3-fold' 1TEL-short-rigid-DARPin crystal. (a) Structure of the `3-fold' 10×His-1TEL-short-rigid-DARPin monomer (PDB entry 9znb), with 1TEL shown in wheat and DARPin in yellow. (b) The unit cell of `3-fold' 10×His-1TEL-short-rigid-DARPin in space group P65 is outlined in black, with symmetry mates displayed in the same colouring as in (a). (c) Crystal lattice representation with 1TEL polymers shown as ribbons and symmetry mates displayed in grey. 1TEL regions are in light grey, DARPin regions are in dark grey and the monomer is coloured as in (a). (d, e) Close-up view of the interactions between the DARPin (yellow) and the adjacent DARPins from neighbouring polymers (dark grey). Proteins are depicted in cartoon representation, with interacting residues shown as sticks and spheres. (f) As in (d) and (e), but showing interactions between the DARPin (yellow) and a 1TEL subunit (light grey) one helical turn above it in the same 1TEL polymer. Also shown are salt-bridge contacts, represented by yellow dotted lines. Figures were prepared using PyMOL (Schrödinger) and Microsoft PowerPoint. |
![[Figure 5]](chr5009fig5.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
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