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![[Figure 2]](nw5134fig2mag.jpg)
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Figure 2
Experimental and predicted oligomeric structures used as a benchmarking set for Alphafuser. (a) Left, PP2A (PDB entry 7soy) with subunits colored uniquely. Right, overlay with the Alphafuser-predicted structure in dark gray. (b) TFIIIC TauA (PDB entry 8clk) colored as per (a). Right, arrows indicate the subunit rotations required to overlay the experimental and predicted structures. (c) TRAPP I (PDB entry 2j3t) colored as per (a). (d) γ-Secretase (PDB entry 6lr4) colored as per (a). Experimental structures are shown in partial transparency on the right for clarity. (e) Plot of ipTM scores for the test cases with the predicted structure corresponding to the experimental structure highlighted in red. In all cases, the experimental structure appeared within the top 10% of predicted complexes ranked by ipTM score. |
![[Figure 2]](nw5134fig2.jpg)
 | STRUCTURAL BIOLOGY |
ISSN: 2059-7983
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