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Figure 6
The single α-helix (SAH) motif of ALC1. (a) Overview of the SAH of ALC1 in the context of the entire structure. The color code is the same as in Fig. 5[link]. The rest of ALC1 and the nucleosome are slightly translucent for clarity. (b, c) Close-up views of the SAH (b) seen from the side and (c) looking down the helical axis. The SAH is colored by conservation. (d) Multiple sequence alignment of ALC1 orthologues verified by structure predictions to have a similar domain architecture to human ALC1, including a putative SAH motif just upstream of the macro domain.

Journal logoSTRUCTURAL
BIOLOGY
ISSN: 2059-7983
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